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Publication Year: 2024

61 to 70 of 579 Results

ETs_seq_mod.fasta Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi Unknown - 43.4 KB - MD5: 5fc33caf3fe27db78e15d93be943ddbb Sequences of the extraterminal (ET) domains in fasta file used in the phylogenetic tree. Secuencias de los dominios extraterminales (ET) en formato fasta utilizados en el árbol filogenético.
ETs_seq_mod_noRedund.fasta Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi Unknown - 18.1 KB - MD5: da1f795e83b3462197edca5d3b03be5b Phylogenetic tree files in fasta format. Archivos de árboles filogenéticos en formato fasta.
ETs_seq_mod_noRedund.fasta.clstr Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi Unknown - 13.3 KB - MD5: b0b3e44257cb3fbf96ea0ab948ec68e9 Non redundant sequences of the extra-terminal (ET) domains in fasta format used in the phylogenetic tree. Secuencias no redundantes de los dominios extraterminales (ET) en formato fasta utilizados en el árbol filogenético.
filtering_analysis.py Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi Python Source Code - 12.9 KB - MD5: 1c795da7041525bbcf7734b77a1a42d6 Filtering strategy for the phylogenetic analysis. Estrategia de filtrado para el analisis filogenético.
final_BD-ET_tree.zip Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi ZIP Archive - 1.3 MB - MD5: e095e8e15199a7326b09b179be023917 Final phylogenetic tree constructed from multiple sequence alignments of the extra-terminal (ET) domains of the bromodomains (BD) selected from the search strategies in Foldseek. Arbol filogenético final contruido a partir de alineamientos de secuencias multiples de los dominios...
finalET_BD_jalviewMSA.fasta Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi Unknown - 33.5 KB - MD5: d4bd394f2c3d487ff018f80e3307d684 Archivo final del alineamiento de secuencias multiples de los dominios extra-terminales (ET) de los bromodominios (BD) en formato fasta. Final file of the multiple sequence alignment of the extra-terminal (ET) domains of bromodomains (BD) in fasta format.
Fluorescence_Polarization.tab Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi Tabular Data - 1.1 KB - 4 Variables, 34 Observations - UNF:6:nzsAXF6SCb6QGtQBi8BX4A== Fluorescence Polarization measurement was performed on a spectrophotometer equipped with a polarizer. Tables include raw data of Polarization versus concentration using the fluorescent probe BSP-AF488. La medición de polarización de la fluorescencia se realizó en un espectrofotóm...
Fluorescence_Quenching_A1B4.tab Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi Tabular Data - 384 B - 11 Variables, 4 Observations - UNF:6:IysjyZ3uTcwm5XXpdYijoQ== Table of three concentrations of A1B4 versus fluorescence intensity from the aromatic amino acids of TcBDF3, TcBD3, TcBD2, and TcBDF3m. As a positive binding control, iBET-151 was used, a BET bromodomain inhibitor previously reported to bind to TcBDF3. Tabla de tres concentrac...
hmmer_commands.sh Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi Shell Script - 147 B - MD5: c12c5eb5759ce13376632d76bdeed7d1 Commands used in the HMMER v3.4 search algorithm. Comandos utilizados en el algoritmo de búsqueda HMMER v3.4.
hmmsearch_output_dom.tab Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi Tabular Data - 82.4 KB - 16 Variables, 772 Observations - UNF:6:FC2Cqf6OhI3z+eOR3H00Ug== Table with the results obtained using the HMMER v3.4 search algorithm. Tabla con los resultados obtenidos utilizando el algoritmo de búsqueda HMMER v3.4.

ETs_seq_mod.fasta

Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi

Unknown - 43.4 KB -

Sequences of the extraterminal (ET) domains in fasta file used in the phylogenetic tree. Secuencias de los dominios extraterminales (ET) en formato fasta utilizados en el árbol filogenético.

ETs_seq_mod_noRedund.fasta

Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi

Unknown - 18.1 KB -

Phylogenetic tree files in fasta format. Archivos de árboles filogenéticos en formato fasta.

ETs_seq_mod_noRedund.fasta.clstr

Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi

Unknown - 13.3 KB -

Non redundant sequences of the extra-terminal (ET) domains in fasta format used in the phylogenetic tree. Secuencias no redundantes de los dominios extraterminales (ET) en formato fasta utilizados en el árbol filogenético.

filtering_analysis.py

Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi

Python Source Code - 12.9 KB -

Filtering strategy for the phylogenetic analysis. Estrategia de filtrado para el analisis filogenético.

final_BD-ET_tree.zip

Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi

ZIP Archive - 1.3 MB -

Final phylogenetic tree constructed from multiple sequence alignments of the extra-terminal (ET) domains of the bromodomains (BD) selected from the search strategies in Foldseek. Arbol filogenético final contruido a partir de alineamientos de secuencias multiples de los dominios...

finalET_BD_jalviewMSA.fasta

Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi

Unknown - 33.5 KB -

Archivo final del alineamiento de secuencias multiples de los dominios extra-terminales (ET) de los bromodominios (BD) en formato fasta. Final file of the multiple sequence alignment of the extra-terminal (ET) domains of bromodomains (BD) in fasta format.

Fluorescence_Polarization.tab

Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi

Tabular Data - 1.1 KB - 4 Variables, 34 Observations -

Fluorescence Polarization measurement was performed on a spectrophotometer equipped with a polarizer. Tables include raw data of Polarization versus concentration using the fluorescent probe BSP-AF488. La medición de polarización de la fluorescencia se realizó en un espectrofotóm...

Fluorescence_Quenching_A1B4.tab

Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi

Tabular Data - 384 B - 11 Variables, 4 Observations -

Table of three concentrations of A1B4 versus fluorescence intensity from the aromatic amino acids of TcBDF3, TcBD3, TcBD2, and TcBDF3m. As a positive binding control, iBET-151 was used, a BET bromodomain inhibitor previously reported to bind to TcBDF3. Tabla de tres concentrac...

hmmer_commands.sh

Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi

Shell Script - 147 B -

Commands used in the HMMER v3.4 search algorithm. Comandos utilizados en el algoritmo de búsqueda HMMER v3.4.

hmmsearch_output_dom.tab

Oct 16, 2024 - Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi

Tabular Data - 82.4 KB - 16 Variables, 772 Observations -

Table with the results obtained using the HMMER v3.4 search algorithm. Tabla con los resultados obtenidos utilizando el algoritmo de búsqueda HMMER v3.4.

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