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Publication Year: 2024

561 to 570 of 582 Results

5_EnvZ_wt_and_variant_activities_Bgal.tab Jul 1, 2024 - Experimental evidence of a new mechanism of activation of bacterial histidine kinases Tabular Data - 3.7 KB - 24 Variables, 27 Observations - UNF:6:ZPUlJAEn/sRUWeYCsfZZZQ== β-galactosidase activity from a PompC-lacZ reporter fusion was measured at low osmolarity (Sucrose 0%) or high osmolarity (Sucrose 15%)
6_DESK_HIS_protein model.pdb Jul 1, 2024 - Experimental evidence of a new mechanism of activation of bacterial histidine kinases application/vnd.palm - 12.7 MB - MD5: a640b7c9c7edebabcbdc6af3497c9dfb DesK structure in the phosphotransfer state (PDB 7JJI), where the H188E mutation was reverted to its WT.
7_DESK_GLU_protein model.pdb Jul 1, 2024 - Experimental evidence of a new mechanism of activation of bacterial histidine kinases application/vnd.palm - 14.0 MB - MD5: 26e5011338644080dc253017b9d892e2 DesK structure in the phosphotransfer state (PDB 7JJI), where the H188E mutation was modified to H188Q.
8_DESK_DESR_WT_complex model.pdb Jul 1, 2024 - Experimental evidence of a new mechanism of activation of bacterial histidine kinases application/vnd.palm - 23.0 MB - MD5: 52c3017fbd2667898741e8de386229f6 Full-length DesK-DesR complex performed by protein-protein docking, using HDOCK server.
9_DESK_DESR_H335Y_complex model.pdb Jul 1, 2024 - Experimental evidence of a new mechanism of activation of bacterial histidine kinases application/vnd.palm - 27.1 MB - MD5: 882c896df053c365b150957752e0cb99 Full-length DesK-DesR complex performed by protein-protein docking, using HDOCK server. The DesK His188 was mutated to tyrosine in silico
Transcription levels of some genes involved in starch metabolism in ChlreSEX4 overexpressing algal lines Apr 24, 2024 - Facultad de Ciencias Bioquímicas y Farmacéuticas Torresi, Florencia; Carrillo, Julieta Beatriz; Gomez-Casati, Diego Fabián; Busi, Maria V.; Martín, Mariana, 2024, "Transcription levels of some genes involved in starch metabolism in ChlreSEX4 overexpressing algal lines", https://doi.org/10.57715/UNR/5TSEDO, RDA UNR, V1, UNF:6:bGlHIV4hObAsW7mDFL7Eiw== [fileUNF] The presented dataset illustrates the transcriptional levels of select genes implicated in starch metabolism within ChlreSEX4 overexpressing algal strains. The analysis of gene expression levels was conducted with the aim of elucidating the impact of upregulating a glucan phospha...
01_Transcription_levels_of_some_genes_involved_in_starch_metabolism_in_ChlreSEX4_overexpressing_algal_lines.tab Apr 24, 2024 - Transcription levels of some genes involved in starch metabolism in ChlreSEX4 overexpressing algal lines Tabular Data - 18.8 KB - 18 Variables, 103 Observations - UNF:6:bGlHIV4hObAsW7mDFL7Eiw== The file displays tables with the relative expression for each studied gene in different algal lines (WT, 13, 24, and 48), with each gene shown in different colors. The column "SAMPLE NAME" indicates which algal line is being analyzed. The column "TARGET NAME" indicates which gen...
02_README.txt Apr 24, 2024 - Transcription levels of some genes involved in starch metabolism in ChlreSEX4 overexpressing algal lines Plain Text - 9.8 KB - MD5: 4681c7ce39772cf1830b9bc4474eb8d8
Supplementary data for: Amino Acids metabolism as drug target for anti-trypanosomatids drug discovery Mar 5, 2024 - Facultad de Ciencias Bioquímicas y Farmacéuticas Labadie, Guillermo; Ballari, María Sol; Damasceno, Flavia S.; Fargnoli, Lucía; Pagura, Lucas; Cricco, Julia A.; Silber, Ariel M., 2024, "Supplementary data for: Amino Acids metabolism as drug target for anti-trypanosomatids drug discovery", https://doi.org/10.57715/UNR/AXNGVK, RDA UNR, V1 Description: Experimental data on the antiparasitic drug discovery project. New compounds characterization data (NMR, UV-Vis, chemoinformatics data) T. cruzi growing curves (IC50, washout experiments) Cell death experiments (flow cytometry) The present dataset is focused in the o...
Ballari_et_al_Supporting_Information_01_T_cruzi_growing_curves.pdf Mar 5, 2024 - Supplementary data for: Amino Acids metabolism as drug target for anti-trypanosomatids drug discovery Adobe PDF - 722.7 KB - MD5: 788733193a5d1ccdd026eba20ae0e960 T cruzi growing curves: effect of the proline analogues on the proliferation of the epimastigote form of T. cruzi Growth curves, dose response curves, and IC50s obtained for treatments of different strains of T. cruzi epimastigotes with variable concentrations of proline analogu...

5_EnvZ_wt_and_variant_activities_Bgal.tab

Jul 1, 2024 - Experimental evidence of a new mechanism of activation of bacterial histidine kinases

Tabular Data - 3.7 KB - 24 Variables, 27 Observations -

β-galactosidase activity from a PompC-lacZ reporter fusion was measured at low osmolarity (Sucrose 0%) or high osmolarity (Sucrose 15%)

6_DESK_HIS_protein model.pdb

Jul 1, 2024 - Experimental evidence of a new mechanism of activation of bacterial histidine kinases

application/vnd.palm - 12.7 MB -

DesK structure in the phosphotransfer state (PDB 7JJI), where the H188E mutation was reverted to its WT.

7_DESK_GLU_protein model.pdb

Jul 1, 2024 - Experimental evidence of a new mechanism of activation of bacterial histidine kinases

application/vnd.palm - 14.0 MB -

DesK structure in the phosphotransfer state (PDB 7JJI), where the H188E mutation was modified to H188Q.

8_DESK_DESR_WT_complex model.pdb

Jul 1, 2024 - Experimental evidence of a new mechanism of activation of bacterial histidine kinases

application/vnd.palm - 23.0 MB -

Full-length DesK-DesR complex performed by protein-protein docking, using HDOCK server.

9_DESK_DESR_H335Y_complex model.pdb

Jul 1, 2024 - Experimental evidence of a new mechanism of activation of bacterial histidine kinases

application/vnd.palm - 27.1 MB -

Full-length DesK-DesR complex performed by protein-protein docking, using HDOCK server. The DesK His188 was mutated to tyrosine in silico

Transcription levels of some genes involved in starch metabolism in ChlreSEX4 overexpressing algal lines

Apr 24, 2024 - Facultad de Ciencias Bioquímicas y Farmacéuticas

Torresi, Florencia; Carrillo, Julieta Beatriz; Gomez-Casati, Diego Fabián; Busi, Maria V.; Martín, Mariana, 2024, "Transcription levels of some genes involved in starch metabolism in ChlreSEX4 overexpressing algal lines", https://doi.org/10.57715/UNR/5TSEDO, RDA UNR, V1, UNF:6:bGlHIV4hObAsW7mDFL7Eiw== [fileUNF]

The presented dataset illustrates the transcriptional levels of select genes implicated in starch metabolism within ChlreSEX4 overexpressing algal strains. The analysis of gene expression levels was conducted with the aim of elucidating the impact of upregulating a glucan phospha...

01_Transcription_levels_of_some_genes_involved_in_starch_metabolism_in_ChlreSEX4_overexpressing_algal_lines.tab

Apr 24, 2024 - Transcription levels of some genes involved in starch metabolism in ChlreSEX4 overexpressing algal lines

Tabular Data - 18.8 KB - 18 Variables, 103 Observations -

The file displays tables with the relative expression for each studied gene in different algal lines (WT, 13, 24, and 48), with each gene shown in different colors. The column "SAMPLE NAME" indicates which algal line is being analyzed. The column "TARGET NAME" indicates which gen...

02_README.txt

Apr 24, 2024 - Transcription levels of some genes involved in starch metabolism in ChlreSEX4 overexpressing algal lines

Plain Text - 9.8 KB -

Supplementary data for: Amino Acids metabolism as drug target for anti-trypanosomatids drug discovery

Mar 5, 2024 - Facultad de Ciencias Bioquímicas y Farmacéuticas

Labadie, Guillermo; Ballari, María Sol; Damasceno, Flavia S.; Fargnoli, Lucía; Pagura, Lucas; Cricco, Julia A.; Silber, Ariel M., 2024, "Supplementary data for: Amino Acids metabolism as drug target for anti-trypanosomatids drug discovery", https://doi.org/10.57715/UNR/AXNGVK, RDA UNR, V1

Description: Experimental data on the antiparasitic drug discovery project. New compounds characterization data (NMR, UV-Vis, chemoinformatics data) T. cruzi growing curves (IC50, washout experiments) Cell death experiments (flow cytometry) The present dataset is focused in the o...

Ballari_et_al_Supporting_Information_01_T_cruzi_growing_curves.pdf

Mar 5, 2024 - Supplementary data for: Amino Acids metabolism as drug target for anti-trypanosomatids drug discovery

Adobe PDF - 722.7 KB -

T cruzi growing curves: effect of the proline analogues on the proliferation of the epimastigote form of T. cruzi Growth curves, dose response curves, and IC50s obtained for treatments of different strains of T. cruzi epimastigotes with variable concentrations of proline analogu...

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