1 to 10 of 10 Results
Oct 23, 2024
Cricco, Julia Alejandra; Mediavilla, María Gabriela; Merli, Marcelo Luciano; Cobine, Paul Antony; Zhu, Xinyu, 2024, "Raw data about control of copper ion homeostasis in Trypanosoma cruzi", https://doi.org/10.57715/UNR/5XIFXN, RDA UNR, V1, UNF:6:9KTk//YxVvcbWQ++3f26FA== [fileUNF]
Introduction: Trypanosoma cruzi, the parasite that causes Chagas disease, requires of essential metabolites and cofactors to guarantee its survival. This parasite must supply its quota of metal ions such as copper (Cu), iron (Fe), calcium (Ca), etc. T. cruzi depends on a mitochon... |
Oct 18, 2024
Di Capua, Cecilia, 2024, "Datos relevados en la encuesta de evaluación de la experiencia de usuario del videojuego educativo Agentes del tiempo", https://doi.org/10.57715/UNR/CLUDBW, RDA UNR, V1, UNF:6:g+cJ0Y+tFDxNdt9QQjeY2Q== [fileUNF]
Introducción Se presentan los datos obtenidos a partir de una encuesta de evaluación de la experiencia de usuario del videojuego educativo Agentes del Tiempo La encuesta fue realizada en el contexto de un trabajo de investigación con el objetivo de evaluar el potencial del videoj... |
Oct 16, 2024
Alonso, Victoria Lucia; Escalante, Andrea Marta; Rodríguez Araya, Elvio; Frattini, Gianfranco; Tavernelli, Luis Emilio; Moreno, Diego M.; Furlan, Ricardo Luis Eugenio; Serra, Esteban Carlos, 2024, "Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi", https://doi.org/10.57715/UNR/NWDOCK, RDA UNR, V1, UNF:6:JMYmZQ1wsnut0WiVlNpu2Q== [fileUNF]
Introduction Targeting lysine acetylation, particularly bromodomain-containing proteins (acetyl-lysine binders), shows promise as a novel antiparasitic target. Our research focuses on TcBDF3, a cytoplasmic bromodomain-containing protein crucial for Trypanosoma cruzi (the causativ... |
Adessi, Tonino G.; Riveira, Martín J.; De La Horra, Camila; Centurión, Enzo F. G., 2024, "1D and 2D Nuclear Magnetic Resonance spectra raw data for the compounds huajiaosimuline and related synthetic and natural pyranoquinolones.", https://doi.org/10.57715/UNR/BVWFGK, RDA UNR, V1
Introduction In the context of natural product synthesis, spectroscopic information has been collected for six compounds of the pyranoquinolone alkaloid type. These include Huajiaosimuline and Simulansine, alkaloids isolated from the species Zanthoxylum simulans, and four synthet... |
Bortolotti, Ana; Almada, Juan Cruz; Porrini, Lucía; Albanesi, Daniela; Miguel, Virginia; Cybulski, Larisa, 2024, "Experimental evidence of a new mechanism of activation of bacterial histidine kinases", https://doi.org/10.57715/UNR/MPA7NB, RDA UNR, V1, UNF:6:MyNjHceGjMJ3qmUD9nYL3Q== [fileUNF]
This data set shows a new mechanism of activation of histidine kinases that participate in signal transduction in bacteria. Experimental evidence was obtained after sequence homology analysis, generation of variant kinases, and their biochemical and structural studies. The techni... |
Apr 24, 2024
Torresi, Florencia; Carrillo, Julieta Beatriz; Gomez-Casati, Diego Fabián; Busi, Maria V.; Martín, Mariana, 2024, "Transcription levels of some genes involved in starch metabolism in ChlreSEX4 overexpressing algal lines", https://doi.org/10.57715/UNR/5TSEDO, RDA UNR, V1, UNF:6:bGlHIV4hObAsW7mDFL7Eiw== [fileUNF]
The presented dataset illustrates the transcriptional levels of select genes implicated in starch metabolism within ChlreSEX4 overexpressing algal strains. The analysis of gene expression levels was conducted with the aim of elucidating the impact of upregulating a glucan phospha... |
Mar 5, 2024
Labadie, Guillermo; Ballari, María Sol; Damasceno, Flavia S.; Fargnoli, Lucía; Pagura, Lucas; Cricco, Julia A.; Silber, Ariel M., 2024, "Supplementary data for: Amino Acids metabolism as drug target for anti-trypanosomatids drug discovery", https://doi.org/10.57715/UNR/AXNGVK, RDA UNR, V1
Description: Experimental data on the antiparasitic drug discovery project. New compounds characterization data (NMR, UV-Vis, chemoinformatics data) T. cruzi growing curves (IC50, washout experiments) Cell death experiments (flow cytometry) The present dataset is focused in the o... |
Bortolotti, Ana; Palavecino, Alejandro; Sartorio, Mariana Gabriela; Carrillo, Néstor; Cortez, Néstor, 2023, "Datos espectroscópicos, cinéticos y fisiológicos de las dos Ferredoxin/flavodoxin-NADP(H) reductasas del aislamiento extremófilo Acinetobacter Ver3", https://doi.org/10.57715/UNR/HETWJ9, RDA UNR, V1, UNF:6:8q3ySl5zvU6gu629Yxe3pQ== [fileUNF]
Este conjunto de datos muestra la participación en la defensa antioxidante, de las dos ferredoxina/flavodoxina NADPH oxidorreductasas de bacterias FPRs y del transportador de electrones flavodoxinaver3 fldver3. Los mismos fueron recolectados tras realizar una caracterización ciné... |
Sep 26, 2023
Biolatto, Silvana; Konjuh, Cintia; Drogo, Claudia; Pacchioni, Alejandra, 2023, "Resultados de encuesta sobre usos y patrones de consumo de sustancias psicoactivas en estudiantes secundarios de la ciudad de Rosario (Santa Fe, Argentina)", https://doi.org/10.57715/UNR/PEFY4Q, RDA UNR, V1, UNF:6:WNs5VcRTmrGL77A0fIv5HA== [fileUNF]
Se presentan los datos de una encuesta realizada en 2016, 2018 y 2019. Los estudiantes que respondieron el cuestionario pertenecían a escuelas de la ciudad de Rosario (Santa Fe, Argentina). Fueron parte de un estudio de extensión universitaria que se desarrolló entre 2013 y 2019.... |
Cybulski, Larisa; Bortolotti, Ana, 2022, "A Transmembrane Histidine Kinase Functions as a pH Sensor", https://doi.org/10.57715/UNR/PTDCEY, RDA UNR, V1, UNF:6:YaedkqRHtqmn6WrA0KUUxA== [fileUNF]
This dataset corresponds to experiments conducted to study the response of transmembrane histidine kinase (DesK) to pH. The two-component system DesK-DesR regulates the synthesis of unsaturated fatty acids in the soil bacteria Bacillus Subtilis. This system is activated at low te... |
