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361 to 370 of 388 Results
Supplementary data for: Amino Acids metabolism as drug target for anti-trypanosomatids drug discovery
Mar 5, 2024
Labadie, Guillermo; Ballari, María Sol; Damasceno, Flavia S.; Fargnoli, Lucía; Pagura, Lucas; Cricco, Julia A.; Silber, Ariel M., 2024, "Supplementary data for: Amino Acids metabolism as drug target for anti-trypanosomatids drug discovery", https://doi.org/10.57715/UNR/AXNGVK, RDA UNR, V1
Description: Experimental data on the antiparasitic drug discovery project. New compounds characterization data (NMR, UV-Vis, chemoinformatics data) T. cruzi growing curves (IC50, washout experiments) Cell death experiments (flow cytometry) The present dataset is focused in the o...
Ballari_et_al_Supporting_Information_01_T_cruzi_growing_curves.pdf
Mar 5, 2024 - Supplementary data for: Amino Acids metabolism as drug target for anti-trypanosomatids drug discovery
Adobe PDF - 722.7 KB - MD5: 788733193a5d1ccdd026eba20ae0e960
T cruzi growing curves: effect of the proline analogues on the proliferation of the epimastigote form of T. cruzi Growth curves, dose response curves, and IC50s obtained for treatments of different strains of T. cruzi epimastigotes with variable concentrations of proline analogu...
Ballari_et_al_Supporting_Information_02_Cell_death_experiments.pdf
Mar 5, 2024 - Supplementary data for: Amino Acids metabolism as drug target for anti-trypanosomatids drug discovery
Adobe PDF - 494.9 KB - MD5: e0f70eccc60536aaffde8227ebd62605
Cell death experiments: cell death analysis for Trypanosoma cruzi epimastigotes. Analysis of cell death and cell cycle arrest mechanisms on T. cruzi epimastigotes caused by treatment with proline analogues. To analyse cell death mechanism, T. cruzi, strain CL14 epimastigotes (2...
Ballari_et_al_Supporting_Information_03_Compounds_Characterization.pdf
Mar 5, 2024 - Supplementary data for: Amino Acids metabolism as drug target for anti-trypanosomatids drug discovery
Adobe PDF - 3.1 MB - MD5: af9f6713537b5c3bb1a9edf1aa659f7c
Compounds characterization. UV-vis characterization of the fluorescent proline analogue 1-NBD, as well as NMR spectral characterization of all final compounds. Prediction of physicochemical properties of fluorescent analogues was performed using molinspiration platform (http://...
Datos espectroscópicos, cinéticos y fisiológicos de las dos Ferredoxin/flavodoxin-NADP(H) reductasas del aislamiento extremófilo Acinetobacter Ver3
Datos espectroscópicos, cinéticos y fisiológicos de las dos Ferredoxin/flavodoxin-NADP(H) reductasas del aislamiento extremófilo Acinetobacter Ver3
Oct 2, 2023
Bortolotti, Ana; Palavecino, Alejandro; Sartorio, Mariana Gabriela; Carrillo, Néstor; Cortez, Néstor, 2023, "Datos espectroscópicos, cinéticos y fisiológicos de las dos Ferredoxin/flavodoxin-NADP(H) reductasas del aislamiento extremófilo Acinetobacter Ver3", https://doi.org/10.57715/UNR/HETWJ9, RDA UNR, V1, UNF:6:8q3ySl5zvU6gu629Yxe3pQ== [fileUNF]
Este conjunto de datos muestra la participación en la defensa antioxidante, de las dos ferredoxina/flavodoxina NADPH oxidorreductasas de bacterias FPRs y del transportador de electrones flavodoxinaver3 fldver3. Los mismos fueron recolectados tras realizar una caracterización ciné...
01_FPRs_Fld_y_Fds_Ver3_aminoacid_sequences.txt
Oct 2, 2023 - Datos espectroscópicos, cinéticos y fisiológicos de las dos Ferredoxin/flavodoxin-NADP(H) reductasas del aislamiento extremófilo Acinetobacter Ver3
Plain Text - 1.2 KB - MD5: 4cba3480ca01d60319b6c33481466e6c
Aminoacid sequences under study from Acinetobacter Ver3
02_FPR1_diferential_spectra.tab
Oct 2, 2023 - Datos espectroscópicos, cinéticos y fisiológicos de las dos Ferredoxin/flavodoxin-NADP(H) reductasas del aislamiento extremófilo Acinetobacter Ver3
Tabular Data - 476.9 KB - 64 Variables, 1362 Observations - UNF:6:3g/0qbdlPBYhkd0QTSBpSA==
FPR1 absorbance data as a function of NADP concentration (0-1)mM. Wavelength range 300-600 nm.
03_FPR2_diferential_spectra.tab
Oct 2, 2023 - Datos espectroscópicos, cinéticos y fisiológicos de las dos Ferredoxin/flavodoxin-NADP(H) reductasas del aislamiento extremófilo Acinetobacter Ver3
Tabular Data - 465.8 KB - 62 Variables, 1353 Observations - UNF:6:C7vrAsVY94CO5Qy+HM2YcA==
FPR2 absorbance data as a function of NADP concentration (0-1)mM. Wavelength range 300-600 nm.
04_Fluorescence_Spectra_FPR1_and_FPR2.tab
Oct 2, 2023 - Datos espectroscópicos, cinéticos y fisiológicos de las dos Ferredoxin/flavodoxin-NADP(H) reductasas del aislamiento extremófilo Acinetobacter Ver3
Tabular Data - 18.2 KB - 22 Variables, 107 Observations - UNF:6:8/rcNpTvNQxDWdbYfWA6Sg==
Fluorescence intensities of FPR1 and FPR2. Excitation spectra between (400-500) nm, fixed emission wavelength 530 nm. Emission spectra between (490-600) nm, fixed excitation wavelength 450 nm. NADP concentration between ( 0-1) mM.
05_Activity_data.tab
Oct 2, 2023 - Datos espectroscópicos, cinéticos y fisiológicos de las dos Ferredoxin/flavodoxin-NADP(H) reductasas del aislamiento extremófilo Acinetobacter Ver3
Tabular Data - 2.2 KB - 13 Variables, 35 Observations - UNF:6:mNvmz5Lr9CQXD7iqyD5jJw==
Kinetic measurements of FPR1 and FPR2. Diaphorase activity with DCPIP and ferricianure as substrate. Cytochromo c reductase with FlavodoxinVer3 as substrate.
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