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Jul 1, 2024 - Facultad de Ciencias Bioquímicas y Farmacéuticas
Bortolotti, Ana; Almada, Juan Cruz; Porrini, Lucía; Albanesi, Daniela; Miguel, Virginia; Cybulski, Larisa, 2024, "Experimental evidence of a new mechanism of activation of bacterial histidine kinases", https://doi.org/10.57715/UNR/MPA7NB, RDA UNR, V1, UNF:6:MyNjHceGjMJ3qmUD9nYL3Q== [fileUNF]
This data set shows a new mechanism of activation of histidine kinases that participate in signal transduction in bacteria. Experimental evidence was obtained after sequence homology analysis, generation of variant kinases, and their biochemical and structural studies. The techni...
Aug 1, 2022 - Facultad de Ciencias Bioquímicas y Farmacéuticas
Cybulski, Larisa; Bortolotti, Ana, 2022, "A Transmembrane Histidine Kinase Functions as a pH Sensor", https://doi.org/10.57715/UNR/PTDCEY, RDA UNR, V1, UNF:6:YaedkqRHtqmn6WrA0KUUxA== [fileUNF]
This dataset corresponds to experiments conducted to study the response of transmembrane histidine kinase (DesK) to pH. The two-component system DesK-DesR regulates the synthesis of unsaturated fatty acids in the soil bacteria Bacillus Subtilis. This system is activated at low te...
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