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Oct 16, 2024 -
Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi
ZIP Archive - 1.3 MB -
MD5: e095e8e15199a7326b09b179be023917
Final phylogenetic tree constructed from multiple sequence alignments of the extra-terminal (ET) domains of the bromodomains (BD) selected from the search strategies in Foldseek.
Arbol filogenético final contruido a partir de alineamientos de secuencias multiples de los dominios... |
Oct 16, 2024 -
Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi
Unknown - 33.5 KB -
MD5: d4bd394f2c3d487ff018f80e3307d684
Archivo final del alineamiento de secuencias multiples de los dominios extra-terminales (ET) de los bromodominios (BD) en formato fasta.
Final file of the multiple sequence alignment of the extra-terminal (ET) domains of bromodomains (BD) in fasta format. |
Oct 16, 2024 -
Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi
Tabular Data - 1.1 KB - 4 Variables, 34 Observations - UNF:6:nzsAXF6SCb6QGtQBi8BX4A==
Fluorescence Polarization measurement was performed on a spectrophotometer equipped with a polarizer. Tables include raw data of Polarization versus concentration using the fluorescent probe BSP-AF488.
La medición de polarización de la fluorescencia se realizó en un espectrofotóm... |
Oct 16, 2024 -
Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi
Tabular Data - 384 B - 11 Variables, 4 Observations - UNF:6:IysjyZ3uTcwm5XXpdYijoQ==
Table of three concentrations of A1B4 versus fluorescence intensity from the aromatic amino acids of TcBDF3, TcBD3, TcBD2, and TcBDF3m. As a positive binding control, iBET-151 was used, a BET bromodomain inhibitor previously reported to bind to TcBDF3.
Tabla de tres concentrac... |
Oct 16, 2024 -
Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi
Shell Script - 147 B -
MD5: c12c5eb5759ce13376632d76bdeed7d1
Commands used in the HMMER v3.4 search algorithm.
Comandos utilizados en el algoritmo de búsqueda HMMER v3.4. |
Oct 16, 2024 -
Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi
Tabular Data - 82.4 KB - 16 Variables, 772 Observations - UNF:6:FC2Cqf6OhI3z+eOR3H00Ug==
Table with the results obtained using the HMMER v3.4 search algorithm.
Tabla con los resultados obtenidos utilizando el algoritmo de búsqueda HMMER v3.4. |
Oct 16, 2024 -
Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi
Plain Text - 142.7 KB -
MD5: e3a4d664cb8d5f4371b26aaa0298a990
Output table of the search using the HMMER v3.4 search algorithm.
Tabla de salida de la búsqueda utilizando el algoritmo de búsqueda HMMER v3.4.
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Oct 16, 2024 -
Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi
Tabular Data - 229 B - 4 Variables, 9 Observations - UNF:6:2RyKD/w3ASTzF6ieve3XzQ==
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction assay determined cell viability after treatment. Table with absorbance measurements at 540 nm for increasing concentrations of A1B4c and A5B4c.
El ensayo de reducción con bromuro de 3-(4,5-dimetiltiaz... |
Oct 16, 2024 -
Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi
Plain Text - 1.6 MB -
MD5: 30faf5671fe2256d955e40431a25cbb0
Identification numbers (ID) of the proteins used in the phylogenetic tree from the National Center for Biotechnology Information (NCBI). Sequences that are included in the Fungi taxonomy group.
Números de identificación (ID) de las proteínas utilizadas en el árbol filogenético d... |
Oct 16, 2024 -
Experimental data on the binding and activity of 1,3,4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi
Plain Text - 13.5 KB -
MD5: ae06d79792e24df59da7e4a59c6530b8
Identification numbers (ID) of the proteins used in the phylogenetic tree from the National Center for Biotechnology Information (NCBI). Sequences that are included in the Kinetoplastidea taxonomic group.
Números de identificación (ID) de las proteínas utilizadas en el árbol fil... |